JURNAL ETNOFARMASI

FORMULASI DAN UJI EFEKTIVITAS SALEP EKSTRAK ETANOL DAUN MANGROVE (Rhizophora mucronata) TERHADAP PENYEMBUHAN LUKA SAYAT PADA MENCIT (Mus muscullus)

Wiwik Triyani Wiwik — 2024-03-31

Mangrove (Rhizophora mucronata) contains flavonoids, saponins and tannins. Compounds contained in mangrove leaves have antiinflammatory, anti viral and antimicrobial activites. Based on the compound, mangrove (Rhizophora mucronata) can be used an ointment for cuts. This study aims to test the preparation of
mangrove leaf ethanol extract ointment on the healing of cuts in mice. The process of extracting mangrove leaves (Rhizophora mucronata) uses the maceration method. In testing the ointment preparations, organoleptic tests, homogeneity tests, pH tests, spreadability tests and viscosity tests were carried out. Testing the effectiveness of wound healing using 5 groups consisting of 3 mice. Each group was giffen different treatment, namale K- was given an ointment base, K+ was given betadine ointment, F1 was given
an ointment with a concetration of 2,5%, F2 was given an ointment with a concentration of 5% and F3 was given an ointment with a concentration of 7,5%. The results showed that the ointment met the standard organoleptic test requirements, test homogeneity, pH test, spreadability test and viscosity test. Based on the results of the incision test on mice, the most effective ointment preparation was a preparation with a concentration of 5%

UJI FISIK SEDIAAN SABUN CAIR EKSTRAK ETANOL DAUN MANGROVE (Rhizophora mucronata)

Rasi Fitri Yanti Tuasikal — 2024-03-31

Caffeic acid, vanillic acid, p-hydroxy benzoic acid, tannins, kau-16-ene, benzophene, phenolic compounds of the flavonoid group, phenolic acids, and dihydroflavonol tannins are all present in mangrove leaves. Alkaloids, coumarins, flavonoids, phenols and polyphenols, quinones, resins, saponins, phytosterols, tannins, xantoprotins, pigments (chlorophyll, carotenoids), and sugars are just some of the substances that can be found in plants. This plant has potential as an antibacterial, antimalarial, antiviral, and antioxidant. The purpose of this study was to obtain the formulation of Mangrove leaf ethanol extract liquid soap preparation and also know the physical properties of black mangroves leaf extract liquid soap preparation. In this study, physical tests of preparations such as organoleptic tests, pH tests, viscosity tests, and foam height tests were carried out. The results in organoleptic test research meet SNI standards, the Ph test has a high pH value of F1 12.71, the dosage properties become more alkaline, the viscosity test results meet SNI standards, while for the high test F3 foam has a high value of 84.91 so that it exceeds the SNI standard.

UJI EFEKTIVITAS DAYA HAMBAT EKSTRAK ETANOL DAUN KASTROLI (Euphorbia Heterophylla, L.) TERHADAP PERTUMBUHAN BAKTERI (Staphylococcus Aureus)

Muhammad Raihan Bagaskara — 2024-03-31

Most infections are caused by bacteria. Bacteria that cause infections will continue to increase and will experience resistance, so it is necessary to optimize therapy, one of which is using plants that have antibacterial activity. The use of plants that have antibacterial properties is one treatment that can be used for infections caused by bacteria. One of the medicinal plants that needs to be developed is katroli (Euphorbia Heterophylla, L.). Traditionally, Indonesian people, especially in Eastern Indonesia, use castor oil as a cure for difficulty defecating. This study aims to determine the effectiveness of ethanol extract of castor leaves (Euphorbia Heterophylla, L.) with concentrations of 12.5 mg, 25 mg, 50 mg to inhibit the growth of bacteria (Staphylococcus Aureus). This research is a type of experimental research carried out using the disc diffusion method. The results of this research showed that there was a transparent zone on each paper disc with the concentration of ethanol extract of castor oil (Euphorbia Heterophylla, L.) known to be at a concentration of 50 mg. The diameter of the largest inhibition zone was 11 mm.

ANALISIS KUALITATIF SENYAWA FORMALDEHYDE PADA TAHU PUTIH YANG BEREDAR DI PASAR KABUPATEN DAN PASAR KOTA SORONG

Nur Hasana Lamarunga — 2024-03-31

Tofu is one of the foods that is very popular with people because it has an economical price and sufficient nutrition, but it does not last long. Formalin is known as a synthetic preservative, but there are still many sellers who add formaldehyde to food, one of which is tofu, in order to extend the shelf life. storage. Formalin should not be added to food, even a small amount because it can cause cancer. The aim of the research is to find out whether the tofu circulating in the Regency market and Sorong City market contains qualitative formaldehyde with chromatophic acid reagent because it effectively binds the formaldehyde so that it is released from the ingredients. The research was carried out. at the UNIMUDA Sorong Integrated Laboratory, using a qualitative method with the addition of chromatogenic acid and sulfuric acid reagents then heated for 15 minutes, if there is a change in color to purple then the sample is declared positive for formalin. A total of 21 tofu samples obtained from 7 markets in Sorong Regency and City did not find formalin compounds.

UJI EFEKTIVITAS ANALGESIK EKSTRAK ETANOL BUAH MERAH (Pandanus conoideus) TERHADAP MENCIT (Mus musculus)

Nazla Wati Sanaky — 2024-03-31

Many traditional plants have analgesic activity and can be used as alternative therapy. One plant that can be used for analgesic activity is Buah Merah (P. conoideus). Red fruit (Pandanus conoideus) is a medicinal plant that is well known and has proven its efficacy. The results of the phytochemical screening of red fruit, contained several active compounds, namely: tannins, flavonoids, saponins and alkaloids. The aim of this research is to determine the effectiveness of red fruit (P. conoideus) ethanol extract in providing an analgesic effect on mice (Mus musculus). This research used an analgesic meter and male mice as experimental animals. Each group was given treatment, the positive control group was given paracetamol, dose group 1 was given
suspension with a concentration of 10%, dose 2 was given suspension with a concentration of 20% and dose group 3 was given 30% suspension then left for 30 minutes then placed on an analgesic meter until the mice writhe, then observe the response that appears. The response of mice from each group was observed for 30, 60, 90 and 120 minutes. The results of the one-way anova test showed that there was an influence and significant differences between the treatment groups. The results show that the ethanol extract of red fruit (P. conoideus) has an analgesic effect on mice (Mus musculus) and a concentration of 20% has the most effective analgesic activity.